CRACKLE

Consortium on Resistance against Carbapenems in Klebsiella Pneumoniae and other Enterobacteriaceae

An observational study that utilizes an existing CRKP consortium consisting of 20 hospitals that are part of 9 different health care systems. The primary objectives were:

1) To determine whether CRKP strain type is associated with outcomes in CRKP infections

2) To evaluate the constellation of clinical and microbiologic factors associated colistin and tigecycline non-suspectibility

3) To explore variation in treatment and outcomes of CRKP infections in various anatomical sites.